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ÀÌ¿øÈï / Lee, Won-Heong
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1995. 3 – 2002. 2 : ¼­¿ï´ëÇб³ ½ÄÇ°°øÇаú, Çлç
2002. 2 – 2009. 2 : ¼­¿ï´ëÇб³ ³ó»ý¸í°øÇкΠ½ÄÇ°»ý¸í°øÇÐÀü°ø, ¹Ú»ç (Áöµµ±³¼ö: ¼­ÁøÈ£ ±³¼ö)
2009. 3 – 2010. 7: ¹Ú»ç ÈÄ ¿¬±¸¿ø, ¼­¿ï´ëÇб³ ³ó¾÷»ý¹°½Å¼ÒÀç ¿¬±¸¼Ò
2010. 7 – 2014. 1: ¹Ú»ç ÈÄ ¿¬±¸¿ø, Àϸ®³ëÀÌ ÁÖ¸³´ëÇб³ Institute for Genomic Biology (Áöµµ±³¼ö: Áø¿ë¼ö ±³¼ö, Michael J Miller ±³¼ö)
2014. 3 – 2018. 2: Á¶±³¼ö, Àü³²´ëÇб³ ¹ÙÀÌ¿À¿¡³ÊÁö°øÇаú
2018. 3 – 2023. 2: ºÎ±³¼ö, Àü³²´ëÇб³ ¹ÙÀÌ¿À¿¡³ÊÁö°øÇаú
2023. 3 – ÇöÀç: ±³¼ö, Àü³²´ëÇб³ ¹ÙÀÌ¿À¿¡³ÊÁö°øÇаú

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    a. ÀçÁ¶ÇÕ ´ëÀå±ÕÀ» ÀÌ¿ëÇÑ GDP-L-fucoseÀÇ »ý»ê

    b. ÀçÁ¶ÇÕ ´ëÀå±ÕÀ» ÀÌ¿ëÇÑ 2'-fucosyllactose(2-FL) »ý»ê


2. ´ë»ç°øÇÐÀûÀ¸·Î ¼³°èµÈ È¿¸ð¸¦ ÀÌ¿ëÇÑ ¹ÙÀÌ¿À¿¬·á »ý»ê

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3. ¹Ì»ý¹° ½Ã½ºÅÛÀ» ÀÌ¿ëÇÑ ¹ÚÅ׸®¿ÀÆÄÁö À¯·¡ ´Ü¹éÁúÀÇ »ý»ê ¹× È°¿ë

   a. ÀçÁ¶ÇÕ ¹Ì»ý¹°(´ëÀå±Õ ¹× È¿¸ð)À» ÀÌ¿ëÇÑ ¿£µµ¶óÀ̽Å(¿ë±Õ¼º ´Ü¹éÁú) »ý»ê

   b. ¹ÙÀÌ¿À¿¡Åº¿Ã »ý»ê°øÁ¤¿¡¼­ ¼¼±Õ¿À¿°ÀÇ ¹æÁö


4. ´ë»ç°øÇÐÀûÀ¸·Î ¼³°èµÈ ´ëÀå±ÕÀ» ÀÌ¿ëÇÑ »ý¹°Àüȯ°øÁ¤ÀÇ °³¹ß

   a. Cyclohexanone monooxygenase¸¦ ¹ßÇöÇÏ´Â ÀçÁ¶ÇÕ ´ëÀå±ÕÀ» ÀÌ¿ëÇÑ

   b. ÀçÁ¶ÇÕ ´ëÀå±Õ¿¡¼­ÀÇ È¿À²ÀûÀÎ NADPH »ýÇÕ¼º ½Ã½ºÅÛÀÇ °³¹ß

1. Won-Heong Lee, Hong Nan, Hyo Jin Kim, Yong-Su Jin (2013) Simultaneous saccharification and fermentaion by engineered Saccharomyces cerevisiae without supplementing extracellular ¥â-glucosidase. Journal of Biotechnology 167:316-322.

 

2. Won-Heong Lee, Jin-Woo Kim, Eun-Hee Park, Nam Soo Han, Myoung-Dong Kim, Jin-Ho Seo (2013) Effects of NADH kinase on NADPH-dependent biotransformation processes in Escherichia coli. Applied Microbiology and Biotechnology 97:1561-1569.

 

3. Won-Heong Lee, Seung-Oh Seo, Yi-Hyun Bae, Hong Nan, Yong-Su Jin, Jin-Ho Seo (2012) Isobutanol production in engineered Saccharomyces cerevisiae by overexpression of 2-ketoisovalerate decarboxylase and valine biosynthetic enzymes. Bioprocess and Biosystems Engineering 35:1467-1475.

 

4. Won-Heong Lee, Panchalee Pathanibul, Josh Quarterman, Jung-Hyun Jo, Nam Soo Han, Michael J. Miller, Yong-Su Jin, Jin-Ho Seo (2012) Whole cell biosynthesis of a functional oligosaccharide, 2¡¯-fucosyllactose, using engineered Escherichia coli. Microbial Cell Factories 11:48.

 

5. Won-Heong Lee, Young-Wook Chin, Nam Soo Han, Myoung-Dong Kim, Jin-Ho Seo (2011) Enhanced production of GDP-l-fucose by overexpression of NADPH regenerator in recombinant Escherichia coli. Applied Microbiology and Biotechnology 91:967-976.